In the early morning of November 4, 1868, with the uprising in Las Clavellinas, Camagüey joined the independence struggle initiated by Carlos Manuel de Céspedes on October 10 at La Demajagua sugar mill.
The uprising was organized by the Revolutionary Board of Camagüey, and after meeting at the planned point early in the morning, the 76 insurgent revolutionaries marched to the sugar mill El Cercado, owned by Martin Castillo Agramonte, where Jeronimo Boza Agramonte was appointed superior military chief of Camagüey, seconded by Gregorio Boza.
The patriots were organized in seven platoons and designated Ignacio Mora de la Pera, Manuel Boza Agramonte, Martín Loynaz Miranda, José Recio Betancourt, Eduardo Agramonte Piña, Francisco Arteaga Piña and Manuel Agramonte Porro as their respective chiefs; Ignacio Agramonte joined them on November 11.
The baptism of fire of the Camagüeyan patriots took place on November 28, when a troop of 800 men of the three arms, led by Blas Villate, Count of Valmaseda, on the way to Nuevitas was ambushed by the Mambises, which forced them to retreat.
The uprising of Las Clavellinas was decisive for the consolidation of the insurrectionary struggle in Cuba, with the patriots of Camagüey in the insurrectionary camp, the Spanish army was forced to change its strategy aimed at suffocating the insurrection in the east of the country.